Sunnybrook Research Institute;The Governing Council of the University of Toronto
发明人:
HAKIMI, Navid,CHENG, Richard Yi-hsiu,SOTOUDEHFAR, Mohammad Hadi,BA, Qing,AMINI-NIK, Saeid,JESCHKE, Marc G.,GUENTHER, Axel
申请号：
EP17857750
公开号：
EP3522828A4
申请日:
2017.10.10
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
Disclosed herein is a bioprinter that enables the in situ formation of architected planar biomaterials and tissues by translating a printer head along a deposition surface, such as skin wounds. In handheld configurations of of the instrument, cell-laden biopolymer solutions are perfused through a moving microfabricated printhead and deposited onto a stationary planar surface or a wound. The printer head may be translated via a drive mechanism. Different embodiments of the instrument are disclosed form vivo application in small animals, as well as for large animal and clinical application. A stationary embodiment of the instrument is well suited for the continuous formation and roll-to-roll processing of planar biomaterials and tissues.
