SUNNYBROOK RESEARCH INSTITUTE;THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
发明人:
HAKIMI, NAVID,CHENG, RICHARD YIHSIU,SOTOUDEHFAR, MOHAMMAD HADI,BA, QING,AMINI-NIK, SAEID,JESCHKE, MARC G.,GUENTHER, AXEL
申请号：
CA3039553
公开号：
CA3039553A1
申请日:
2017.10.10
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Disclosed herein is a bioprinter that enables the in situ formation of architected planar biomaterials and tissues by translating a printer head along a deposition surface, such as skin wounds. In handheld configurations of of the instrument, cell-laden biopolymer solutions are perfused through a moving microfabricated printhead and deposited onto a stationary planar surface or a wound. The printer head may be translated via a drive mechanism. Different embodiments of the instrument are disclosed for m vivo application in small animals, as well as for large animal and clinical application. A stationary embodiment of the instrument is well suited for the continuous formation and roll-to-roll processing of planar biomaterials and tissues.
