SUNNYBROOK RESEARCH INSTITUTE;THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
发明人:
Navid HAKIMI,Richard Yihsiu CHENG,Mohammad Hadi SOTOUDEHFAR,Qing BA,Saeid AMINI-NIK,Marc G. JESCHKE,Axel GUENTHER
申请号:
US16340327
公开号:
US20200040291A1
申请日:
2017.10.10
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed herein is a bioprinter that enables the in situ formation of architected planar biomaterials and tissues by translating a printer head along a deposition surface, such as skin wounds. In handheld configurations of of the instrument, cell-laden biopolymer solutions are perfused through a moving microfabricated printhead and deposited onto a stationary planar surface or a wound. The printer head may be translated via a drive mechanism. Different embodiments of the instrument are disclosed form vivo application in small animals, as well as for large animal and clinical application. A stationary embodiment of the instrument is well suited for the continuous formation and roll-to-roll processing of planar biomaterials and tissues.