PHARMACEUTICAL COMPOSITION COMPRISING AN EXTRACT OF PSEUDOLYSIMACHION LONGIFOLIUM AND THE CATALPOL DERIVATIVES ISOLATED THEREFROM HAVING ANTIINFLAMMATORY, ANTIALLERGIC AND ANTIASTHMATIC ACTIVITY
LEE HYEONG KYU,OH SEI RYANG,LEE SANG KU,KWON OK KYOUNG,JOUNG HYOUK,QUAN GUI HUA,KIM MI JIN,PARK BO YOUNG,AHN KYUNG SEOP,LEE JOONG KU
申请号：
IN9757/DELNP/2007
公开号：
IN254672B
申请日:
2007.12.17
申请国别(地区):
IN
年份:
2012
代理人:
摘要：
The present invention relates to a composition comprising an extract of Pseudolysimachion genus plant, and the catalpol derivatives isolated therefrom having anti-inflammatory, antiallergic and anti-asthmatic activity. The extract of Pseudolysimachion genus plant and the catalpol derivatives isolated therefrom shows potent suppressing effect on elevated IgE, IL-4 and IL- 13 levels and eosinophilia in the plasma and BALF, and mucus overproduction in the lung tissues in an OVA-induced asthmatic mouse model. Therefore, it can be used as the therapeutics or functional health food for treating and preventing inflammatory, allergic and asthmatic disease.
