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3H-thieno[3,4]pyrimidin-4-one and pyrrolopyrimidone as gram-positive antibacterial agents
专利权人:
发明人:
申请号:
EP14305283.5
公开号:
EP2913333A1
申请日:
2014.02.27
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The invention relates to novel heteroaromatic derivatives of formula (I) and their addition salts thereof with acids and bases their preparation, their use as drugs and pharmaceutical compositions and associations containing them.wherein A, B, T, V, X and Y represent organic substituents as defined herein,The compounds of formula (I) are able to inhibit the activity of the Gram-positive bacterial DltA enzyme and they are used to prevent and/or treat Gram-positive bacterial infections in humans or animals, alone or in association with antibacterials, antivirulence agents or drugs reinforcing the host innate immunity,
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