SMART BRAIN S.R.O.;BIOTECHNOLOGICKY USTAV AV CR, V.V.I.
发明人:
JAROSLAV TRUKSA,Lukas WERNER,Jan STURSA
申请号：
US16613644
公开号：
US20200078379A1
申请日:
2018.07.13
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The deferoxamine derivatives of general formula I and pharmaceutically acceptable salts thereof, at least one of R1 and R2 is a substituent of formula II. The novel derivatives are particularly suitable as medicaments, preferably for the treatment of cancer. Pharmaceutical preparations of compounds of formula I and a metal, preferably gallium, are also provided resulting in even more active medicaments or contrast agents. Combinations with other agents, resulting in synergistic effects are provided.
