Pharmaceutical composition comprising an extract of Pseudolysimachion longifolium and the catalpol derivatives isolated therefrom having antiinflammatory, antiallergic and antiasthmatic activity
Hyeong Kyu Lee;Sei Ryang Oh;Kyung Seop Ahn;Sang Ku Lee;Joong Ku Lee;Ok Kyoung Kwon;Doo Young Kim;Hyouk Joung;Gui Hua Quan;Mi Jin Kim;Bo Young Park
发明人:
Hyeong Kyu Lee,Sei Ryang Oh,Kyung Seop Ahn,Sang Ku Lee,Joong Ku Lee,Ok Kyoung Kwon,Doo Young Kim,Hyouk Joung,Gui Hua Quan,Mi Jin Kim,Bo Young Park
申请号：
US13427334
公开号：
US08974837B2
申请日:
2012.03.22
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to a composition comprising an extract of Pseudolysimachion genus plant, and the catalpol derivatives isolated therefrom having anti-inflammatory, anti-allergic and anti-asthmatic activity. The extract of Pseudolysimachion genus plant and the catalpol derivatives isolated therefrom shows potent suppressing effect on elevated IgE, IL-4 and IL-13 levels and eosinophilia in the plasma and BALF, and mucus overproduction in the lung tissues in an OVA-induced asthmatic mouse model. Therefore, it can be used as the therapeutics or functional health food for treating and preventing inflammatory, allergic and asthmatic disease.
