PHARMACEUTICAL COMPOSITION COMPRISING AN EXTRACT OF PSEUDOLYSIMACHION LONGIFOLIUM AND THE CATALPOL DERIVATIVES ISOLATED THEREFROM HAVING ANTIINFLAMMATORY, ANTIALLERGIC AND ANTIASTHMATIC ACTIVITY
Mi Jin KIM;Sei Ryang-Oh;Ok Kyoung KWON;Hyeong Kyu LEE;Bo Young PARK;Sang Ku LEE;Joong Ku LEE;Doo Young KIM;Kyung Seop AHN;Hyouk JOUNG;Gui Hua QUAN
发明人:
Hyeong Kyu LEE,Sei Ryang-Oh,Kyung Seop AHN,Sang Ku LEE,Joong Ku LEE,Ok Kyoung KWON,Doo Young KIM,Hyouk JOUNG,Gui Hua QUAN,Mi Jin KIM,Bo Young PARK
申请号：
US13427352
公开号：
US20120184499A1
申请日:
2012.03.22
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to a composition comprising an extract of Pseudolysimachion genus plant, and the catalpol derivatives isolated therefrom having anti-inflammatory, anti-allergic and anti-asthmatic activity. The extract of Pseudolysimachion genus plant and the catalpol derivatives isolated therefrom shows potent suppressing effect on elevated IgE, IL-4 and IL-13 levels and eosinophilia in the plasma and BALF, and mucus overproduction in the lung tissues in an OVA-induced asthmatic mouse model. Therefore, it can be used as the therapeutics or functional health food for treating and preventing inflammatory, allergic and asthmatic disease.
