WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH;ST. VINCENTS INSTITUTE OF MEDICAL RESEARCH;ST. VINCENT'S INSTITUTE OF MEDICAL RESEARCH
发明人:
STRASSER, ANDREAS,MCKENZIE, MARK,THOMAS, HELEN,ALLISON, JANETTE,KAY, TOM
申请号：
EP09804387
公开号：
EP2331135A4
申请日:
2009.08.05
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
The present invention relates to a method for treating and/or preventing a disease associated with glucose toxicity in a subject which may comprise administering to the subject a compound that reduces the level of Bim, PUMA and/or Bax activity in a cell of the subject. Furthermore, provided is a method for culturing cells susceptible to exposure to high concentrations of glucose, which may comprise delivering to the cells, or progenitor cells thereof, a compound that reduces the level of Bim, PUMA and/or Bax activity in the cells.
