Walter and Eliza Hall Institute of Medical Research;St Vincent's Institute of Medical Research
发明人:
Strasser, Andreas,McKenzie, Mark,Thomas, Helen,Allison, Janette,Kay, Tom
申请号：
AU2009279375
公开号：
AU2009279375B2
申请日:
2009.08.05
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
The present invention relates to a method for treating and/or preventing a disease associated with glucose toxicity in a subject which comprises administering to the subject a compound that reduces the level of Bim, PUMA and/or Bax activity in a cell of the subject. Furthermore, provided is a method for culturing cells susceptible to exposure to high concentrations of glucose, which comprises delivering to the cells, or progenitor cells thereof, a compound that reduces the level of Bim, PUMA and/or Bax activity in the cells.
