DAMUDE, HOWARD, GLENN,XUE, ZHIXIONG,ZHU, QUINN, QUN,POLLAK, DANA M. WALTERS
申请号:
DK07794950
公开号:
DK2021478T3
申请日:
2007.05.16
申请国别(地区):
DK
年份:
2012
代理人:
摘要:
The present invention relates to a &Dgr;5 desaturase, which has the ability to convert dihomo-γ-linolenic acid (DGLA; 20:3 ω-6) to arachidonic acid (ARA; 20:4 ω-6) and/or eicosatetraenoic acid (ETA; 20:4 ω-3) to eicosapentaenoic acid (EPA; 20:5 ω-3). Isolated nucleic acid fragments and recombinant constructs comprising such fragments encoding &Dgr;5 desaturase along with a method of making long chain polyunsaturated fatty acids (PUFAs) using this &Dgr;5 desaturase in oleaginous yeast are disclosed.