DELTA-5 DESATURASE AND ITS USE IN THE MANUFACTURE OF MULTIPLE-UNSATURATED FATTY ACIDS

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专利权人:

E.I. DU PONT DE NEMOURS AND COMPANY

发明人:

DAMUDE, HOWARD,POLLAK, DANA,XUE, ZHIXIONG,ZHU, QUINN

申请号：

AT07794926

公开号：

AT544858T

申请日:

2007.05.16

申请国别(地区):

AT

年份:

2012

代理人:

摘要：

The present invention relates to a &Dgr；5 desaturase, which has the ability to convert dihomo-&gamma；-linolenic acid (DGLA； 20:3 &omega；-6) to arachidonic acid (ARA； 20:4 &omega；-6) and/or eicosatetraenoic acid (ETA； 20:4 &omega；-3) to eicosapentaenoic acid (EPA； 20:5 &omega；-3). Isolated nucleic acid fragments and recombinant constructs comprising such fragments encoding &Dgr；5 desaturase along with a method of making long chain polyunsaturated fatty acids (PUFAs) using this &Dgr；5 desaturase in oleaginous yeast are disclosed.

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