RINDERSPACHER KIRSTEN ALISON,YU WAI,DUFF KAREN,LANDRY DONALD,DENG SHI XIAN
申请号:
IN201847016353
公开号:
IN201847016353A
申请日:
2018.05.01
申请国别(地区):
IN
年份:
2018
代理人:
摘要:
ABSTRACT ACTIVATORS OF AUTOPHAGIC FLUX AND PHOSPHOLIPASE D AND CLEARANCE OF PROTEIN AGGREGATES INCLUDING TAU AND TREATMENT OF PROTEINOPATHIES The present application discloses compounds which are activators of autophagic flux and pharmaceutical compositions comprising said activators. It further discloses use of said compounds and pharmaceutical compositions in the treatment of neurodegenerative diseases, particularly proteinopathies and tauopathies such as Alzheimers disease. It further discloses methods of enhancing autophagic flux. Figure 1