THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK;NY STATE PSYCHIATRIC INSTITUTE
发明人:
Kirsten Alison Rinderspacher,Wai Yu,Karen Duff,Donald Landry,Shi-Xian Deng
申请号:
US15480220
公开号:
US10487091B2
申请日:
2017.04.05
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present application discloses compounds which are activators of autophagic flux and pharmaceutical compositions comprising said activators. It further discloses use of said compounds and pharmaceutical compositions in the treatment of neurodegenerative diseases, particularly proteinopathies and tauopathies such as Alzheimer's disease. It further discloses methods of enhancing autophagic flux.