Activators of autophagic flux and phospholipase D and clearance of protein aggregates including tau and treatment of proteinopathies

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专利权人:

The Trustees of Columbia University in the City of New York;NY State Psychiatric Institute

发明人:

Rinderspacher, Kirsten Alison,Yu, Wai,Duff, Karen,Landry, Donald,Deng, Shi-Xian

申请号：

AU2016333987

公开号：

AU2016333987A1

申请日:

2016.10.05

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

The present application discloses compounds which are activators of autophagic flux and pharmaceutical compositions comprising said activators. It further discloses use of said compounds and pharmaceutical compositions in the treatment of neurodegenerative diseases, particularly proteinopathies and tauopathies such as Alzheimer's disease. It further discloses methods of enhancing autophagic flux.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/