The present disclosure is directed to compositions and methods for the prevention, treatment, and/or functional cure of HIV infection. One aspect of the present disclosure relates to monoclonal antibodies directed against CD4, compositions thereof, and methods employing such compositions for the prevention, treatment, and functional cure of HIV infection.本發明有關於用以預防、治療,及/或功能性治癒HIV感染的組成物和方法。本發明之一範疇是關於針對CD4之單株抗體、其組成物,以及使用此組成物以預防、治療,和功能性治癒HIV感染的方法。