A monoclonal antibody inhibiting immunosuppressive functions of pathogens, antigen-binding fragments thereof, and hybridomas producing such antibody农业专利-农业学术服务平台

摘要：: The present invention relates to a monoclonal that inhibits immunosuppressive functions of pathogens, antigen-binding fragments thereof, and hybridomas producing such antibody. The monoclonal antibody or antigen-binding fragments thereof bind to a peptide consisting an amino acid sequence represented by or similar to MEKVGKDGVITVE (SEQ ID NO: 1). The present invention also discloses use of the invented monoclonal antibody or antigen-binding fragments thereof, and method of preparation for such hybridomas.本發明提供一種具有抑制致病原的免疫抑制功能的單株抗體,其抗原結合片段,以及產生該等抗體的融合瘤。該單株抗體或其抗原結合片段,係與MEKVGKDGVITVE(序列編號1)所表示或其相似之胺基酸序列所構成之胜肽結合。本發明並揭示該單株抗體及其抗原結合片段的用途,以及該融合瘤的製法。