НОВАРТИС АГ (CH);РИДЖЕНТС ОФ ДЗЕ ЮНИВЕРСИТИ ОФ МИННЕСОТА (US)
发明人:
САВЧУК Рональд Дж. (US),ЧЕУНГ Белинда В.Й. (US),УОЛЛ Дж. Майкл (US)
申请号：
RU2016101214
公开号：
RU2016101214A
申请日:
2011.01.07
申请国别(地区):
RU
年份:
2018
代理人:
摘要：
Methods and materials useful for applying moxifloxacin to the ear are described. The methods involve delivering a composition that contains at least one viscogenic agent and moxifloxacin or a salt thereof to the epidermal surface of the tympanic membrane via the ear canal. The composition is delivered to the tympanic membrane in a flowable form and, after delivery to the tympanic membrane, becomes sufficiently viscous such that the moxifloxacin is localized against the tympanic membrane. Such compositions can be used to prophylactically and/or therapeutically treat middle and inner ear conditions, including otitis media.
