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ENGINEERING THE PRODUCTION OF A CONFORMATIONAL VARIANT OF OCCIDIOFUNGIN THAT HAS ENHANCED INHIBITORY ACTIVITY AGAINST FUNGAL SPECIES
专利权人:
The Texas A&;M University System;Mississippi State University
发明人:
JAMES LEIF SMITH,AKSHAYA RAVICHANDRAN,SHIEN LU,GANYU GU
申请号:
US16403123
公开号:
US20190270777A1
申请日:
2019.05.03
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Occidiofungin is a cyclic nonribosomally synthesized antifungal peptide with submicromolar activity. This invention is directed to compositions enriched for particular occidiofungin diastereomers/conformers, methods of making compositions enriched for particular diastereomers/conformers and microorganisms suitable for producing enriched compositions of particular diastereomers/conformers. Methods of treating fungal infections or plants infected by fungi are also provided.
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