Colin M. Tice;Wei He;Yuanjie Ye;Gerard McGeehan;Wei Zhao;Katerina Leftheris;Zhenrong Xu;Salvacion Cacatian;Linghang Zhuang;Suresh B. Singh;David A. Claremon
发明人:
David A. Claremon,Wei He,Gerard McGeehan,Suresh B. Singh,Colin M. Tice,Zhenrong Xu,Yuanjie Ye,Wei Zhao,Linghang Zhuang,Salvacion Cacatian,Katerina Leftheris
申请号：
US12670205
公开号：
US08575156B2
申请日:
2008.07.25
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Disclosed are compounds represented by Formula (I):or pharmaceutically acceptable salts, enantiomers or diastereomers thereof. Also disclosed are pharmaceutical compositions comprising the compounds of Formula (I) or pharmaceutically acceptable salts, enantiomers or diastereomers thereof and methods of inhibiting 11β-HSD1 activity comprising the step of administering to a mammal in need of such treatment an effective amount of a compound of Formula (I), or a pharmaceutically acceptable salt, enantiomer or diastereomer thereof. Values for the variables in Formula (I) are defined herein.
