2-[4-(PIRAZOL-4-ILALQUIL)PIPERAZIN-1-IL]-3-FENIL-PIRAZINAS E -PIRIDINAS E 3-[4-(PIRAZOL-4-ILALQUIL)PIPERAZIN-1-IL]-2- FENIL-PIRIDINAS COMO ANTAGONISTAS DO RECETOR 5-HT7

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专利权人:

ELI LILLY AND COMPANY

发明人:

JOHN MEHNERT SCHAUS,MICHAEL PHILIP COHEN,PATRICK GIANPIETRO SPINAZZE,SANDRA ANN FILLA,SARAH LYNNE HELLMAN,VALENTINA O. BADESCU,PETER THADDEUS GALLAGHER,MARIA ANN WHATTON,ANNE MARIE CAMP,BARRY PETER CL

申请号：

PT08747748

公开号：

PT2155717E

申请日:

2008.05.07

申请国别(地区):

PT

年份:

2012

代理人:

摘要：

The present invention provides selective 5-HT7 receptor antagonist compounds of Formula I and their use in the treatment of migraine, persistent pain, and anxiety: where A and B are each independently &mdash；C(H)&boxH； or &mdash；N&boxH；, provided that at least one of A and B is &mdash；N&boxH；, n is 1-3, m is 0-3, and R1-4 are as defined herein.

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