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Dipyridylamine derivative
专利权人:
LIMITED;DAIICHI SANKYO COMPANY
发明人:
KANEKO, SATORU,TSURUOKA, HIROYUKI,HONZUMI, MASATOSHI,ABE, MANABU,YOSHIDA, TAISHI
申请号:
TW101107807
公开号:
TW201247649A
申请日:
2012.03.08
申请国别(地区):
TW
年份:
2012
代理人:
摘要:
The subject of the present invention is related to a compound having excellent glucokinase activating effect, or pharmaceutically acceptable salt thereof. The solution of the present invention is a compound presented by formula (I) or pharmaceutically acceptable salt thereof. (wherein R1 is a C6-C10 aryl group optionally independently substituted with one to five groups selected from substituent group A, a C1-C6 alkyl group optionally independently substituted with one to five groups selected from substituent group B, etc.; X is a single bond, an oxgen atom, a sulfur atom, etc.; R2 is a C6-C10 aryl group optionally independently substituted with one to five groups selected from substituent group A, etc.; R3 is 1H-tetrazole-5-yl or 5-oxo-4, 5-dihydro-[1, 2, 4]oxadiazole-3-yl; substituent group A is the group consisting of a halogen atom, a C1-C6 alkyl group, a halogenated C1-C6 alkyl group, a hydroxyl group, and a C1-C6 hydoxyalkyl group, etc.; substituent group B is the group consisting of a halogen atom, a C3-C6 cycloalkyl group optionally substituted with a C1-C6 hydroxyalkyl group, a hydroxyl group, a C1-C6 alkoxy group, a C2-C7 alkylcarbonyl group, and a C2-C7 alkoxycarbonyl group, etc.).
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