ROBERT CARR,STEFAN HILDBRAND,MARK L. HODGES,MICHAEL KAMMERER,JOHN F. LANG,WILLIAM J. LAWRIMORE III,DIEU NGUYEN
申请号：
PT13725159
公开号：
PT2855497T
申请日:
2013.05.27
申请国别(地区):
PT
年份:
2016
代理人:
摘要：
An improved process for the preparation of (2R)-2-deoxy-2-fluoro-2-methylcytidine derivatives of formula I wherein R1 is selected from C1-4-alkyl is described. The (2R)-2-deoxy-2-fluoro-2-methylcytidine derivatives of formula I have the potential to be useful as prodrugs for potent inhibitors of the Hepatitis C Virus (HCV) NS5B polymerase.
