CARR, ROBERT,HILDBRAND, STEFAN,HODGES, MARK L.,KAMMERER, MICHAEL,LANG, JOHN F.,LAWRIMORE III, WILLIAM J.,NGUYEN, DIEU
申请号：
SG11201406945Q
公开号：
SG11201406945QA
申请日:
2013.05.27
申请国别(地区):
SG
年份:
2014
代理人:
摘要：
An improved process for the preparation of (2R)-2-deoxy-2-fluoro-2-methylcytidine derivatives of formula I, (I), wherein R1 is selected from C1-4-alkyl is described. The (2R)-2-deoxy-2-fluoro-2-methylcytidine derivatives of formula I have the potential to be useful as prodrugs for potent inhibitors of the Hepatitis C Virus (HCV) NS5B polymerase.
