DESHPANDE, MILIND,WILES, JASON ALLAN,HASHIMOTO, AKIHIRO,PHADKE, AVINASH
申请号:
CA2909273
公开号:
CA2909273A1
申请日:
2014.04.14
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
Deuterated nucleoside analogs of Formula (I) and the pharmaceutically acceptable salts thereof are provided by this disclosure Formula (I) The variables, e.g., B1, Y, R1, R2, R3, R3', R4, R5, R6, R7, R8, and R9 carry definitions set forth in the disclosure. Compounds of Formula (I) are deuterated at one or more positions and the deuterium enrichment at each deuterated positions is at least 50%. Compounds and salts of Formula (I) are useful for treating viral infections, including HCV infections.