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DEUTERATED NUCLEOSIDE PRODRUGS USEFUL FOR TREATING HCV
专利权人:
Inc.;Achillion Pharmaceuticals
发明人:
Milind Deshpande,Jason Allan Wiles,Akihiro Hashimoto,Avinash Phadke
申请号:
US14252494
公开号:
US20140309164A1
申请日:
2014.04.14
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Deuterated nucleoside analogs of Formula (I) and the pharmaceutically acceptable salts thereof are provided by this disclosureThe variables, e.g., B1, Y, R1, R2, R3, R3′, R4, R5, R6, R7, R8, and R9 carry definitions set forth in the disclosure. Compounds of Formula (I) are deuterated at one or more positions and the deuterium enrichment at each deuterated positions is at least 50%. Compounds and salts of Formula (I) are useful for treating viral infections, including HCV infections.
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