Milind Deshpande,Jason Allan Wiles,Akihiro Hashimoto,Avinash Phadke
申请号：
US14252290
公开号：
US09447132B2
申请日:
2014.04.14
申请国别(地区):
US
年份:
2016
代理人:
摘要：
A deuterated nucleoside analog of the formulaand the pharmaceutically acceptable salts thereof are provided by this disclosure. The disclosure also includes pharmaceutical compositions comprising a compound or salt of the formula and a carrier. Compounds and salts of this formula are useful for treating viral infections, including HCV infections. A method for treating a host afflicted with hepatitis C or other disorders is also presented that includes administering an effective treatment amount of a nucleoside or nucleotide that has deuterium with at least 50% enrichment at the 5′-position of the nucleoside or nucleotide.
