Deshpande, Milind,Wiles, Jason Allan,Hashimoto, Akihiro,Phadke, Avinash
申请号：
AU2014250762
公开号：
AU2014250762A1
申请日:
2014.04.14
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
A deuterated nucleoside analog of the formula and the pharmaceutically acceptable salts thereof are provided by this disclosure. The disclosure also includes pharmaceutical compositions comprising a compound or salt of the formula and a carrier. Compounds and salts of this formula are useful for treating viral infections, including HCV infections. A method for treating a host afflicted with hepatitis C or other disorders is also presented that includes administering an effective treatment amount of a nucleoside or nucleotide that has deuterium with at least 50% enrichment at the 5'-position of the nucleoside or nucleotide.
