Generation of antibodies to tumor antigens and generation of tumor specific complement dependent cytotoxicity by administration of oncolytic vaccinia virus

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专利权人:

Inc.;SillaJen

发明人:

Kirn, David,Bell, John,Breitbach, Caroline,Moon, Anne,Hwang, Tae-Ho,Lee, Yu Kyoung,Kim, Mi-Kyung

申请号：

AU2012204467

公开号：

AU2012204467A2

申请日:

2012.01.04

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

The present invention relates to methods and compositions for use in inducing tumor-specific antibody mediated complement-dependent cytotoxic response in an animal having a tumor comprising administering to said animal a composition comprising a replication competent oncolytic virus wherein administration of the composition induces in the animal production of antibodies that mediate a CDC response specific to said tumor.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/