Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling

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专利权人:

发明人:

申请号：

EP08020208.8

公开号：

EP2106800B1

申请日:

1996.12.04

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

T Cell activation in response to antigen is increased by the administration of binding agents that block CTLA-4 signaling. When CTLA-4 signaling is thus blocked, the T cell response to antigen is released from inhibition. Such an enhanced response is useful for the treatment of tumors, chronic viral infections, and as an adjuvant during immunization.

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