Frédéric Gilbert LABÉGUÈRE,Rama HENG,Frédéric André DE CEUNINCK,Luke Jonathan ALVEY,David AMANTINI,Franck Laurent BREBION,Pierre Marc Marie Joseph DEPREZ,Romain Luc Marie GOSMINI,Hélène Marie JARY,Chr
申请号：
US16308380
公开号：
US20190300503A1
申请日:
2017.06.01
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention discloses compounds according to Formula I:Wherein R1, R2, R3a, R3b, R6, Cy, and the subscript n are as defined herein.The present invention relates to compounds inhibiting ADAMTS, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of inflammatory diseases, and/or diseases involving degradation of cartilage and/or disruption of cartilage homeostasis by administering the compound of the invention.
