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MÉDICAMENT CIBLANT UNE CELLULE SOUCHE CANCÉREUSE
专利权人:
Sumitomo Dainippon Pharma Co.; Ltd.
发明人:
申请号:
EP17884516.0
公开号:
EP3560494A1
申请日:
2017.12.20
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
The present invention provides an anti-tumor agent comprising a compound of formula (1) or a pharmaceutically acceptable salt thereof, wherein ring Q1 is optionally-substituted C6-10 aryl, etc.; R1 and R2 are independently hydrogen atom, etc.; W1 is C1-4 alkylene which may be optionally substituted with 1 to 3 fluorine atoms or C3-7 cycloalkyl; W2 is -NR4aC(O)-, etc. wherein R4a is hydrogen atom or C1-6 alkyl; ring Q2 is optionally-substituted C6-10 aryl, etc., in combination with at least one agent selected from the group consisting of an anti-cancer agent, an anti-diabetic agent, an agent for treating dyslipidemia, an agent for treating multiple sclerosis, a steroidal anti-inflammatory agent, a non-steroidal anti-inflammatory agent, an anti-fungal agent, and a pharmaceutically acceptable salt thereof.
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