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AGENT FOR REMOVING UNDIFFERENTIATED iPS CELLS
专利权人:
Ltd.;Sumitomo Dainippon Pharma Co.
发明人:
Yasushi Hiramine,Masayo Fujiwara,Hitoshi Ban,Futoshi Hasegawa
申请号:
US16471474
公开号:
US20190390172A1
申请日:
2017.12.19
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention provides a compound of formula (1) or a salt thereof wherein ring Q1 is optionally-substituted C6-10 aryl, etc.; R1 and R2 are independently hydrogen atom, etc.; W1 is C1-4 alkylene which may be optionally substituted with 1 to 3 fluorine atoms or C3-7 cycloalkyl; W2 is —;NR4aC(O)—;, etc. wherein R4a is hydrogen atom or C1-6 alkyl; ring Q2 is optionally-substituted C6-10 aryl, etc., which has an inhibitory effect on the sphere-forming ability of cancer cells and is useful an agent for removing iPS cells.
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