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METHOD FOR PRODUCING MEGAKARYOCYTES AND/OR PLATELETS FROM PLURIPOTENT STEM CELLS
专利权人:
发明人:
申请号:
EP12838198.5
公开号:
EP2765187A1
申请日:
2012.10.03
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
An agent for inducing production of megakaryocytes and/or platelets from pluripotent stem cells which is useful for treatment of disease accompanied by a decrease in platelets is provided.A method for producing megakaryocytes and/or platelets, comprising separating hematopoietic progenitor cells from the septal cells in sac-like structures produced by pluripotent stem cells, and culturing the hematopoietic progenitor cells ex vivo in the presence of a compound represented by the formula (I) (wherein R1 to R7, W, X, Y, Z, Ar1 and n are as defined in the description) to differentiate them into megakaryocytes and/or platelets.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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