JOSEPHUS JOHANNES DE KIMPE;ANNEMIEKE AARTSMA-RUS;GERARDUS JOHANNES PLATENBURG;JUDITH CHRISTINA THEODORA VAN DEUTEKOM;GARRIT-JAN BOUDEWIJN VAN OMMEN
发明人:
JOSEPHUS JOHANNES DE KIMPE,GERARDUS JOHANNES PLATENBURG,JUDITH CHRISTINA THEODORA VAN DEUTEKOM,ANNEMIEKE AARTSMA-RUS,GARRIT-JAN BOUDEWIJN VAN OMMEN
申请号：
US13094548
公开号：
US20120022134A1
申请日:
2011.04.26
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to a method for inducing or promoting skipping of exon 45 of DMD pre-mRNA in a Duchenne Muscular Dystrophy patient, preferably in an isolated (muscle) cell, the method comprising providing said cell with a molecule that binds to a continuous stretch of at least 21 nucleotides within said exon. The invention further relates to such molecule used in said method.
