PINGALI, HARIKISHORE,MAKADIA, PANKAJ,PANDYA, VRAJESH,KALAPATAPU, V. V. M. SAIRAM,JAIN, MUKUL R.
申请号：
ES11818931
公开号：
ES2535244T3
申请日:
2011.12.26
申请国别(地区):
ES
年份:
2015
代理人:
摘要：
Compounds of formula (I) ** Formula ** their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, where 'A' represents an optionally substituted single or condensed group selected from aryl, heterocyclyl or cycloalkyl groups； 'Y' represents a linear or branched, substituted or unsubstituted (C-C6) alkyl (C2-C6) alkyl or groups or groups represented by '-U (CH2) m-' where U represents O, S ( O) or, NR4； 'm' represents whole numbers from 2 to 4, 'or' represents whole numbers from 0 to 2 and R4 represents H, substituted or unsubstituted linear or branched (C1-C6) alkyl； 'Z' represents an optionally substituted single or condensed group selected from aryl, heterocyclyl or cycloalkyl groups； 'X' represents a link, or is selected from O, S (O) or or NR4； where R4 is as defined above； 'W' represents linear or branched, substituted or unsubstituted (C-C6) alkyl, (C2-C6) alkenyl groups； R1 represents hydrogen, optionally substituted groups, (C1-C6) alkyl, (C3-C6) cycloalkyl, alkoxyalkyl, hydroxyalkyl, aminoalkyl, aryl, heterocyclyl, aralkyl, heterocyclylalkyl； R2 represents hydrogen, or the groups selected from (C1-C6) alkyl, aryl, heterocyclyl, aralkyl, heterocyclylalkyl, (C1-C6) alkoxy, hydroxyalkyl, thioalkyl (C1-C6), amino, aminoalkyl, alkylamino, each of the which may be optionally substituted； or R1 and R2, when possible, may together form a saturated 4- or 7-membered saturated or partially saturated ring containing 4-2 heteroatoms selected from the group comprising N, O, and S (O) or； R3 independently represents at each occurrence hydrogen, halogen, (C1-C3) alkyl, halo (C1-C3) alkyl, (C1-C3) alkoxy, (C1-C3) thioalkyl, sulfenyl derivatives, sulfonyl derivatives； 'n' represents whole numbers from 0-3.Compuestos de fórmula (I)**Fórmula** sus formas tautoméricas, sus estereoisómeros, sus sales farmacéuticamente aceptables, donde 'A' representa un grupo sencillo o condensado opcionalmente sustituido seleccionado entre grupos arilo, heterociclilo
