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Derivatives of triazine and uracil, their preparation, and their application in human therapeutics
专利权人:
ピエール、ファーブル、メディカマン
发明人:
イザベル、リロイ,エリザベート、ドュポン‐パセレーグ,カリーヌ、バレイユ,イブ、リバル,ディディエ、ジュンケロ
申请号:
JP2011517863
公开号:
JP5599788B2
申请日:
2009.07.07
申请国别(地区):
JP
年份:
2014
代理人:
摘要:
The present invention relates to derivatives of general formula I wherein: -W represents nitrogen, -R1 represents: .a hydrogen or a linear or branched C1-C5 alkyl radical or, .a C1-C3 alkyl radical substituted with groups such as trifluoromethyl, nitrile, hydroxy, C1-C3 alcoxy, C3-C6 alkoxyalkoxy, indolyl, thiophenyl, oxothiophenyl, C1-C3 N-alkylcarbamoyl groups or, .a phenyl or pyridyl or naphthyl, or thiophenyl group optionally substituted with one or more groups such as halogen atoms, nitro, nitrile, trifluoromethyl, vinyl, methylsulfanyl, linear branched C1-C4 alkyl, linear or branched C1-C3 alkoxy groups, .a C6 2-oxocycloalkyl radical-R2 represents a methyl or heptyl, -m, n are equal to 1, -V represents CH2, -X-Y represents -N- (C=O)-, -CH-O-, -Z represents a phenyl group substituted with one or more trifluoromethyl groups, halogen atoms or linear C1-C4 alkyl groups.
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