A polypeptide, a nucleic acid molecule encoding the polypeptide and a pharmaceutical composition comprising the polypeptide are provided. The polypeptide is as defined in the description and can bind to an insulin receptor, and is effective in reducing blood sugar, reducing glycated hemoglobin, and ameliorating hepato-renal disorders caused by diabetic.一種多胜肽、編碼該多胜肽之核酸分子、以及包含該多胜肽之醫藥組合物,其中,該多胜肽具如說明書之定義,可與胰島素受體結合,且具有降血糖、降低醣化血色素及減少糖尿病肝腎病變等功效。
