WOLLERT, Kai Christoph,卡伊.克里斯托夫.沃勒特,KORFKLINGEBIEL, Mortimer,莫蒂默.科尔夫克林格比尔,莫蒂默.科爾夫克林格比爾
申请号:
MOJ004064
公开号:
MOJ004064B
申请日:
2020.03.10
申请国别(地区):
MO
年份:
2020
代理人:
摘要:
The present invention relates to proteins (called factor 1 and / or factor 2) or inhibitors thereof containing amino acid sequences encoded by nucleic acids derived from human chromosome regions c19orf10 and / or c19orf63, which are used to enhance the proliferation and / or healing of non transformed tissues or cells and / or inhibit their apoptosis. The invention also relates to the use of inhibitors of factor 1 and factor 2 for medical purposes, preferably for the treatment or prevention of diseases in which angiogenesis contributes to the occurrence or progression of diseases.本發明涉及包含由來源於人染色體區C19Orf10和/或C19Orf63的核酸編碼的氨基酸序列的蛋白質(稱爲因子1和/或因子2)或者其抑制劑,所述蛋白質用於增強非轉化組織或非轉化細胞的增殖和/或使其癒合和/或抑制其凋亡。本發明還涉及因子1和因子2的抑制劑用於醫學用途的用途,優選用於治療或預防其中血管發生有助於疾病發生或進展之疾病的用途。