Holz, Josefin-Beate,Rossenu, Stefaan,De Bruyn, Steven,Sargentini-Maier, Maria Laura,Yalkinoglu, Özkan
申请号：
AU2017201367
公开号：
AU2017201367A1
申请日:
2017.02.28
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
#$%^&*AU2017201367A120170316.pdf#####ABSTRACT Pblypeptides are provided directed against IL-6Rat specific dose ranges and dosing schedules that result in aprolonged effect on IL-6 mediated signaling. In particular, the invention provides pharmacologically active agents, compositions, methods and/or dosing schedules that have certain advantages compared to the agents, compositions, methods and/or dosing schedules that are currently used and/or known in the art, including the ability to dose less frequently or to administer lower doses to obtain equivalent effects in inhibiting IL-6 mediated signaling.
