HOLZ, Josefin-Beate,ROSSENU, Stefaan,DE BRUYN, Steven,SARGENTINI-MAIER, Maria Laura,YALKINOGLU, Özkan
申请号：
DK12766309
公开号：
DK2747782T3
申请日:
2012.09.24
申请国别(地区):
DK
年份:
2018
代理人:
摘要：
Polypeptides are provided directed against IL-6R at specific dose ranges and dosing schedules that result in a prolonged effect on IL-6 mediated signaling. In particular, the invention provides pharmacologically active agents, compositions, methods and/or dosing schedules that have certain advantages compared to the agents, compositions, methods and/or dosing schedules that are currently used and/or known in the art, including the ability to dose less frequently or to administer lower doses to obtain equivalent effects in inhibiting IL-6 mediated signaling.
