REVA MEDIKAL, INK.; INK.;REVA MEDIKAL;REVA MEDICAL INC
发明人:
BALUKA Ehrnest G. (US),БАЛУКА Эрнест Г. (US),BALUKA EHRNEST G.
申请号：
RU2009112529/04
公开号：
RU0002461582C2
申请日:
2007.10.16
申请国别(地区):
RU
年份:
2012
代理人:
摘要：
FIELD: chemistry.SUBSTANCE: invention relates to N-substituted monomers and polymers, methods of producing such monomers and polymers and methods for their use for different medical purposes, e.g., in medical devices. Disclosed is a polymer which contains a repeating unit of formula (I), where X1 and X2 are independently selected from Br and I； y1 and y2 are equal to zero or an integer from 1 to 4, A1 is selected from a group consisting of , , , and , R3 is selected from C1-C30 alkyl, and C1-C30 heteroalkyl, C5-C30 aryl, C6-C30 alkylaryl and C2-C30 heteroaryl； R4 is selected from H, C1-C30 alkyl and C1-C30 heteroalkyl； R1 is (A) or (B)； Z is O or S； R5 and R6 are selected from -CH=CH-, -CHJ1-CHJ2- and -(CH2)a-； a equals zero or an integer from 1 to 8； J1 and J2 are independently selected from H, Br and I； Q is a group which contains 20 or more carbon atoms； Rx is selected from optionally substituted branched or straight C7-C30 alkyl and optionally substituted C6-C30 aryl； and Ry is selected from hydrogen, optionally substituted branched or straight C1-C30 alkyl and optionally substituted C6-C30 aryl. Also disclosed are versions of said polymer, methods of producing said polymers and a medical device containing the disclosed polymers. The medical device is preferably a stent.EFFECT: disclosed polymer has improved physical and chemical properties and is suitable for use in implantable medical devices.31 cl, 1 dwg, 2 tbl, 3 exИзобретение относится к N-замещенным мономерам и полимерам, способам получения таких мономеров и полимеров и способам их использования для различных медицинских целей, например в медицинских устройствах. Предложен полимер, содержащий повторяющееся звено формулы (I), где X1 и X2 независимо выбраны из Br и I； у1 и у2 равны нулю или целому числу от 1 до 4, А1 выбирают из группы, состоящей из, , , и ；R3 выбирают из С1-С30алкила, и C1-С30гетероалкила, С5-С30арила, С6-С30алкиларила и С2-С30гетероарила； R4 выбирают из Н, C1-С30алкила и C1-С30гетер
