PLATTNER, JACOB J.,GIORDANO, ILARIA,ALLEY, M. R. K.,HERNANDEZ, VICENTE S.,BARROS-AGUIRRE, DAVID,LI, XIANFENG
申请号：
PE0002342016
公开号：
PE07522016A1
申请日:
2014.08.08
申请国别(地区):
PE
年份:
2016
代理人:
摘要：
Provide anti mycobacterial compounds of formula II and formula IIA where X is chlorine, Fluorine, Bromine or iodine R1 and R2 are h, CH3, ch2ch2ch3 - CH2CH3, -, or - ch (CH3) 2. Preferred compounds are: (3 - bromo - 7.8 - 2H - 1,6,9 - trioxa - 9th - borabenzo - [CD] - Blue - 2 - il) - metanamina (S) (3 - bromo - 7.8 - 2H - 1,6,9 - trioxa - 9th - borabenzo - [CD] - Blue - 2 - il) - metanamina among others.It also relates to compositions containing. These compounds are derived from benzoxaborol tricyclic being useful in the treatment of mycobacterial infection in a MammalSe proporcionan compuestos anti-micobacterianos de Formula II y Formula IIa donde X es cloro, fluor, bromo o yodo R1 y R2 son H, -CH3, -CH2CH3, -CH2CH2CH3, o -CH(CH3)2. Son compuestos preferidos: (3-bromo-7,8-2H-1,6,9-trioxa-9a-borabenzo-[cd]-azulen-2-il)-metanamina (S)(3-bromo-7,8-2H-1,6,9-trioxa-9a-borabenzo-[cd]-azulen-2-il)-metanamina entre otros. Tambien se refiere a composiciones que los contienen. Dichos compuestos son derivados de benzoxaborol triciclicos siendo utiles en el en el tratamiento de una infeccion micobacteriana en un mamifero
