ALLEY, M. R. K. (dickon),BARROS-AGUIRRE, David,GIORDANO, Ilaria,HERNANDEZ, Vincent,LI, Xianfeng,PLATTNER, Jacob J.
申请号：
PE0014002017
公开号：
PE14322017A1
申请日:
2016.02.12
申请国别(地区):
PE
年份:
2017
代理人:
摘要：
Benzoxaborol relates to compounds of formula (iii), where X is Fluorine, Chlorine, Bromine or iodine R1 and R2 are h, CH3, ch2ch2ch3 CH2CH3 -, - or - ch (CH3) 2 or a Salt or hydrate thereof.It is a selected Compound (S) (3 - Chloro - 7.8 - dihydro - 2H - 1, 6.9-trioxa-9a-borabenzo - [CD] - Blue - 2 - il) - metanamida among others. It also relates to pharmaceutical compositions containing same.These compounds are anti mycobacterial, being useful in the treatment of tuberculosisSe refiere a compuestos de benzoxaborol de formula (III), donde X es fluor, cloro, bromo o yodo R1 y R2 son H, -CH3, -CH2CH3, -CH2CH2CH3 o -CH(CH3)2 o una sal o hidrato del mismo. Es un compuesto seleccionado: (S)(3-cloro-7,8-dihidro-2H-1,6.9-trioxa-9a-borabenzo-[cd]-azulen-2-il)-metanamida entre otros. Tambien se refiere a composiciones farmaceuticas que los comprenden. Dichos compuestos son anti-micobacterianos, siendo utiles en el tratamiento de tuberculosis
