GLAXOSMITHKLINE INTELLECTUAL PROPERTY (No.2) LIMITED;ANACOR PHARMACEUTICALS, INC.
发明人:
ALLEY, M. R. K. (dickon),BARROS-AGUIRRE, David,GIORDANO, Ilaria,HERNANDEZ, Vincent,LI, Xianfeng,PLATTNER, Jacob J.
申请号：
PE2017001400
公开号：
PE20171432A1
申请日:
2016.02.12
申请国别(地区):
PE
年份:
2017
代理人:
摘要：
It refers to benzoxaborol (III) compounds containing fluorine, chlorine, bromine or iodine； R1 and R2 are h, CH3, ch2ch3, ch2ch3 or CH3 (CH3) 2 or salt or hydrate thereof. It is a selected compound: (s) (3-chloro-7, 8-dihydro-2h-1, 6.9-trioxa-9a-borabenzo - [CD] - azulen-2-il) - metabolite, etc. He also refers to pharmacology composers who understand them These compounds are antifungal and are used in the treatment of tuberculosisSe refiere a compuestos de benzoxaborol de formula (III), donde X es fluor, cloro, bromo o yodo； R1 y R2 son H, -CH3, -CH2CH3, -CH2CH2CH3 o -CH(CH3)2 o una sal o hidrato del mismo. Es un compuesto seleccionado: (S)(3-cloro-7,8-dihidro-2H-1,6.9-trioxa-9a-borabenzo-[cd]-azulen-2-il)-metanamida； entre otros. Tambien se refiere a composiciones farmaceuticas que los comprenden. Dichos compuestos son anti-micobacterianos, siendo utiles en el tratamiento de tuberculosis
