PROBLEM TO BE SOLVED: To provide a keratinocyte migration promoter which is useful for quick healing of a wound, or an external preparation composition or a pharmaceutical composition for healing a wound.SOLUTION: This invention relates to: a keratinocyte migration promoter containing a Citrus Tamurana form Orange Hyuganatu extract, a water-soluble component of the Citrus Tamurana form Orange Hyuganatu extract, or a fraction having a molecular weight of 2,000-200,000 obtained by gel filtration chromatography from the Citrus Tamurana form Orange Hyuganatu extract as an active ingredient or an external preparation composition or a pharmaceutical composition containing the keratinocyte migration promoter.COPYRIGHT: (C)2014,JPO&INPIT【課題】速やかな傷の治癒に有用なケラチノサイト遊走促進剤、または創傷を治癒するのに有用な外用剤組成物又は医薬品組成物の提供。【解決手段】ヒュウガナツ(日向夏)抽出物、ヒュウガナツ抽出物の水溶性成分、またはヒュウガナツ抽出物よりゲル濾過クロマトグラフィーにて得られる分子量2000~20万の画分を有効成分とするケラチノサイト遊走促進剤、またはケラチノサイト遊走促進剤を含有する外用剤組成物若しくは医薬品組成物。【選択図】なし
