PROBLEM TO BE SOLVED: To provide an external pharmaceutical composition excellent in effect for improving or treating conditions of affected area receiving damage and deletion and effectively improving or treating diseases which become factors and to provide a method for enhancing wound-healing effect of a wound-healing promotor.SOLUTION: This external pharmaceutical composition comprises a wound-healing promotor, an antifungal agent having high affinity for keratin and a humectant. The method for enhancing wound-healing effect of the wound-healing promotor comprises formulating the wound-healing promotor with the antifungal agent having high affinity for keratin and the humectant.COPYRIGHT: (C)2008,JPO&INPIT【課題】損傷や欠損を受けた患部の状態を改善又は治療する効果に優れ、要因となる疾患を効率よく改善又は治療する外用医薬組成物を提供すること、および、創傷治療促進剤の創傷治癒効果を高める方法を提供すること。【解決手段】創傷治癒促進剤、ケラチン親和性の高い抗真菌剤及び保湿剤を含有する外用医薬組成物、および、創傷治癒促進剤とケラチン親和性の高い抗真菌剤および保湿剤とを組み合わせて配合することを含む、前記創傷治癒促進剤の創傷治癒効果を増強する方法。【選択図】なし