Problem to be solved: to provide a skin storage improving agent and an antifungal external preparation containing the same.Solution: the skin storage improving agent of antifungal agent containing a lipid peptide type compound comprising at least one of the compounds represented by the following formula (1) or a pharmaceutically available salt thereof and fatty acid.1In formula (R1), R1 represents an aliphatic group of 9 to 23 carbon atoms, R2 represents a hydrogen atom or an alkyl group of 1 to 4 carbon atoms that can have a branched chain of 1 or 2 carbon atoms, wherein R3 represents - (CH2) N-X groups, and N represents 1 to X represents an amino group, a guanidino group, a - CONH2 group, or a fused heterocyclic ring consisting of a five membered or six membered ring or five membered ring and six membered ring capable of having one to three nitrogen atomsNo selection【課題】皮膚貯留性改善剤及びこれを含む抗真菌外用製剤を提供する。【解決手段】 下記式(1)で表される化合物又はその薬学的に使用可能な塩のうちの少なくとも一種からなる脂質ペプチド型化合物と脂肪酸とを含有する、抗真菌薬の皮膚貯留性改善剤。【化1】(式中、R1は炭素原子数9乃至23の脂肪族基を表し、R2は水素原子、又は炭素原子数1若しくは2の分枝鎖を有し得る炭素原子数1乃至4のアルキル基を表し、R3は-(CH2)n-X基を表し、nは1乃至4の数を表し、Xはアミノ基、グアニジノ基、-CONH2基、又は窒素原子を1乃至3個有し得る5員環若しくは6員環又は5員環と6員環から構成される縮合複素環を表す。)【選択図】なし
