PROBLEM TO BE SOLVED: To provide a fibroblast migration promoter which is useful for novel and quick healing of a wound, or an external preparation composition or a pharmaceutical composition for healing a wound.SOLUTION: This invention relates to: a fibroblast migration promoter containing a natural and safe plant: Citrus Tamurana form Orange Hyuganatu extract as an active ingredient or an external preparation composition or a pharmaceutical composition containing the fibroblast migration promoter. The fibroblast migration promoter preferably contains a fraction having a molecular weight of 2,000-200,000 obtained by gel filtration chromatography from the Citrus Tamurana form Orange Hyuganatu extract as an active ingredient.COPYRIGHT: (C)2014,JPO&INPIT【課題】新規で速やかな傷の治癒に有用な線維芽細胞遊走促進剤又は、創傷を治癒するのに有用な外用剤組成物又は医薬品組成物を提供すること。【解決手段】天然であり且つ安全な植物:ヒュウガナツ抽出物を有効成分とする線維芽細胞遊走促進剤、又は、線維芽細胞遊走促進剤を含有する外用剤組成物又は医薬品組成物。該線維芽細胞遊走促進剤は、ヒュウガナツ抽出物よりゲル濾過クロマトグラフィーにて得られる分子量2000~20万の画分を有効成分とすることが好ましい。【選択図】なし