ACIDE (1R,6S)-2-AZABICYCLO[4.3.0] NONANE-8,8-DIPHOSPHONIQUE ET SON UTILISATION DANS LE TRAITEMENT OU LA PREVENTION DES TROUBLES OSSEUX, PAR EXEMPLE L'OSTEOPOROSE OU LA MALADIE DE PAGET
THE PROCTER & GAMBLE COMPANY;UNIVERSITY OF ROCHESTER
发明人:
EBETINO, FRANK HALLOCK,BOECKMAN, ROBERT KENNETH, JR.,SONG, XINYI
申请号：
CA2672191
公开号：
CA2672191C
申请日:
2007.12.14
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
Disclosed is a new composition of matter, substantially enantiomerically pure (1R,6S)-2-Azabicyclo-[4.3.0]nonane-8,8-diphosphonic acid, methods of preparing this new composition of matter, a pharmaceutical composition comprising the new composition, and administration of the composition in methods of treating bone disorders such as osteoporosis, osteolytic bone metastasis, rheumatoid arthritis and osteoarthritis.
